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Implantation Technique Influences LV Remodeling After TMVR

Favorable remodeling, as seen on CT, is more likely when the apical pad of the Tendyne system is closer to the true apex.

Transcatheter mitral valve replacement (TMVR) with the Tendyne system (Abbott) results in anatomic and functional improvements in the left side of the heart within a month of the procedure, with the gains related to how the device is implanted, a CT-based study demonstrates.

The prosthesis is held in place by a tether attached to an apical pad, and when that pad was placed closer to the true apex, it was predictive of a decrease in LV end-diastolic volume. Moreover, significant reductions in LV end-diastolic volume, LV mass, and left atrial volume were seen when the pad was placed in a distal-apical location, but not when it was in a mid-apical location.

This is the first study to demonstrate these changes in anatomy and function with a comprehensive

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